[Free.CuVG] Therapeutic Immunosuppression (Immunology and Medicine Volume 29)
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Book Details :
Published on: 2001-07-31
Released on:
Original language: English
Therapeutic immunosuppression has very broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (e.g., rheumatoid arthritis), skin disease, and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential. In addition, products of the biotechnology industry - monoclonal antibodies, cytokines, cytokine antagonists, and other products of genetic engineering that target key molecular pathways in disease pathogenesis - have either already made, or are on the verge of making an important impact on treatment. There is also considerable interest in the potential of cell-based therapies (particularly hematopoietic stem and dendritic cell therapy) of allo- and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. Gene therapy offers considerable promise for suppressing pathogenic processes in either transplantation or autoimmune disorders. The possibility of combining these important new advances to maximize benefit to the patient, and to minimize possible untoward effects (which are also given extensive coverage in this book), is one of the most exciting challenges of contemporary medicine. This volume is intended both for practising physicians and surgeons and for biomedical scientists at the graduate/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppression, and to provide state-of-the-art reviews of current developments in each area. Each chapter is contributed by one or more experts in the field. There was a need to bring this information together in a single volume, as much of the key recent developments have been dispersed throughout the biomedical literature, largely in specialized journals. Since, as in the past, important developments in immunosuppressive therapy in one branch of medicine (i.e. transplantation) are likely to benefit another (e.g., dermatology, rheumatology, gastroenterology), cross-disciplinary coverage of the mechanistic basis of the various therapeutic strategies in a single volume is likely to convey the potential of advances in therapy in the most coherent manner possible. The IL-23-IL-17 immune axis: from mechanisms to ... Abstract Key points Introduction Cytokines that promote T H 17 cell development Transcriptional control of T H 17 cells T H 17 cell plasticity ... Immunogenic Cell Death in Cancer Therapy Annual Review ... INTRODUCTION. Every second in the healthy human adult several millions of cells that succumb to programmed cell death mechanisms are efficiently removed without ... NIAAA Publications Alcoholic Lung Disease Corey D. Kershaw M.D. and David M. Guidot M.D. Corey D. Kershaw M.D. is assistant professor of Medicine and David M. Guidot M.D. is ... Home : Nature Reviews Immunology Animation: Immunology of the rheumatoid joint. Rheumatoid arthritis is an inflammatory disease that mainly affects the joints in which the body's immune system ... Sepsis - Wikipedia There are different levels of sepsis: sepsis severe sepsis and septic shock. In 2016 screening by systemic inflammatory response syndrome (SIRS) was replaced with ... Rabbit Antithymocyte Globulin versus Basiliximab in Renal ... Original Article. Rabbit Antithymocyte Globulin versus Basiliximab in Renal Transplantation. Daniel C. Brennan M.D. John A. Daller M.D. Ph.D. Kathleen D. Lake ... A Randomized Placebo-Controlled Trial of Natalizumab for ... Of a total of 942 patients 627 were randomly assigned to receive natalizumab (at a dose of 300 mg) and 315 to receive placebo by intravenous infusion every four ... Cardiology Conferences 2017 Events Las Vegas USA ... Meet top & best Cardiologists cardiac Surgeons physicians doctors nursing & health care professionals at Cardiology congress Conferences events meetings ... Volume 144 Issue 4_MeetingAbstracts CHEST Journal ... SESSION TITLE: Airway Case Report Posters. SESSION TYPE: Affiliate Case Report Poster. PRESENTED ON: Tuesday October 29 2013 at 01:30 PM - 02:30 PM
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